USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: Q96H20 USC-OGP 2-DE database:  Q96H20 Q96H20 General information about the entry View entry in simple text format Entry name SNF8_HUMAN Primary accession number Q96H20 Secondary accession number(s) Q9UN50 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Vacuolar-sorting protein SNF8; AltName: Full=ELL-associated protein of 30 kDa; AltName: Full=ESCRT-II complex subunit VPS22; Short=hVps22;. Gene name Name=SNF8 Synonyms=EAP30 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1269: pI=6.38; Mw=28709 Cross-references UniProtKB/Swiss-Prot Q96H20; SNF8_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name SNF8_HUMAN Primary accession number Q96H20 Secondary accession number(s) Q8IXY3 Q9UN50 Sequence was last modified on  December 1, 2001 (version 1) Annotations were last modified on  March 15, 2017 (version 138) Name and origin of the protein Description RecName: Full=Vacuolar-sorting protein SNF8; AltName: Full=ELL-associated protein of 30 kDa; AltName: Full=ESCRT-II complex subunit VPS22; Short=hVps22; Gene name Name=SNF8 Synonyms=EAP30 Encoded on Name=SNF8; Synonyms=EAP30 Keywords 3D-structure; Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Endosome; Membrane; Methylation; Nucleus; Protein transport; Reference proteome; Transcription; Transcription regulation; Transport. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF156102; AAD46560.1; -; mRNA EMBL BC008976; AAH08976.1; -; mRNA EMBL BC038830; AAH38830.1; -; mRNA CCDS CCDS11541.1; -. [Q96H20-1]; . CCDS CCDS82156.1; -. [Q96H20-2]; . RefSeq NP_001304121.1; NM_001317192.1. [Q96H20-2]; . RefSeq NP_001304122.1; NM_001317193.1; . RefSeq NP_001304123.1; NM_001317194.1; . RefSeq NP_009172.2; NM_007241.3. [Q96H20-1]; . UniGene Hs.127249; -; . PDB 2ZME; X-ray; 2.90 A; A=1-258 PDB 3CUQ; X-ray; 2.61 A; A=25-258 PDBsum 2ZME; -; . PDBsum 3CUQ; -; . ProteinModelPortal Q96H20; -; . SMR Q96H20; -; . BioGrid 116425; 42; . IntAct Q96H20; 25; . MINT MINT-5001874; -; . STRING 9606.ENSP00000421380; -; . iPTMnet Q96H20; -; . PhosphoSitePlus Q96H20; -; . BioMuta SNF8; -; . DMDM 73919323; -; . EPD Q96H20; -; . MaxQB Q96H20; -; . PaxDb Q96H20; -; . PeptideAtlas Q96H20; -; . PRIDE Q96H20; -; . DNASU 11267; -; . Ensembl ENST00000290330; ENSP00000290330; ENSG00000159210. [Q96H20-2]; . Ensembl ENST00000502492; ENSP00000421380; ENSG00000159210. [Q96H20-1]; . GeneID 11267; -; . KEGG hsa:11267; -; . UCSC uc002ioj.5; human. [Q96H20-1]; . CTD 11267; -; . DisGeNET 11267; -; . GeneCards SNF8; -; . H-InvDB HIX0135631; -; . HGNC HGNC:17028; SNF8; . HPA HPA059320; -; . MIM 610904; gene; . neXtProt NX_Q96H20; -; . OpenTargets ENSG00000159210; -; . PharmGKB PA142670892; -; . eggNOG KOG3341; Eukaryota; . eggNOG ENOG410XPVM; LUCA; . GeneTree ENSGT00390000007843; -; . HOGENOM HOG000170930; -; . HOVERGEN HBG079872; -; . InParanoid Q96H20; -; . KO K12188; -; . OMA QMSKQLE; -; . OrthoDB EOG091G0GWO; -; . PhylomeDB Q96H20; -; . TreeFam TF105950; -; . Reactome R-HSA-917729; Endosomal Sorting Complex Required For Transport (ESCRT); . ChiTaRS SNF8; human; . EvolutionaryTrace Q96H20; -; . GeneWiki SNF8; -; . GenomeRNAi 11267; -; . PRO PR:Q96H20; -; . Proteomes UP000005640; Chromosome 17; . Bgee ENSG00000159210; -; . CleanEx HS_SNF8; -; . ExpressionAtlas Q96H20; baseline and differential; . Genevisible Q96H20; HS; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0005829; C:cytosol; IDA:UniProtKB; . GO GO:0010008; C:endosome membrane; IDA:UniProtKB; . GO GO:0000814; C:ESCRT II complex; TAS:ParkinsonsUK-UCL; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0031902; C:late endosome membrane; IDA:UniProtKB; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005654; C:nucleoplasm; IDA:HPA; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB; . GO GO:0005886; C:plasma membrane; IDA:UniProtKB; . GO GO:0055037; C:recycling endosome; IDA:UniProtKB; . GO GO:0005667; C:transcription factor complex; IDA:MGI; . GO GO:0016247; F:channel regulator activity; IDA:UniProtKB; . GO GO:0008022; F:protein C-terminus binding; IPI:UniProtKB; . GO GO:0042803; F:protein homodimerization activity; IPI:UniProtKB; . GO GO:0047485; F:protein N-terminus binding; IPI:UniProtKB; . GO GO:0008134; F:transcription factor binding; IDA:MGI; . GO GO:0045022; P:early endosome to late endosome transport; IMP:UniProtKB; . GO GO:0032456; P:endocytic recycling; IMP:UniProtKB; . GO GO:0016197; P:endosomal transport; TAS:Reactome; . GO GO:0016236; P:macroautophagy; TAS:ParkinsonsUK-UCL; . GO GO:0036258; P:multivesicular body assembly; TAS:ParkinsonsUK-UCL; . GO GO:0071985; P:multivesicular body sorting pathway; TAS:ParkinsonsUK-UCL; . GO GO:1903543; P:positive regulation of exosomal secretion; IMP:UniProtKB; . GO GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB; . GO GO:0045732; P:positive regulation of protein catabolic process; IMP:UniProtKB; . GO GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IBA:GO_Central; . GO GO:0010797; P:regulation of multivesicular body size involved in endosome transport; IMP:UniProtKB; . GO GO:0042176; P:regulation of protein catabolic process; IMP:UniProtKB; . GO GO:0061635; P:regulation of protein complex stability; IMP:UniProtKB; . GO GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI; . GO GO:1903772; P:regulation of viral budding via host ESCRT complex; IMP:UniProtKB; . GO GO:0006351; P:transcription; DNA-templated; IEA:UniProtKB-KW Gene3D 1.10.10.10; -; 2; . InterPro IPR007286; EAP30; . InterPro IPR016689; ESCRT-2_cplx_Snf8; . InterPro IPR011991; WHTH_DNA-bd_dom; . PANTHER PTHR12806; PTHR12806; 1; . Pfam PF04157; EAP30; 1; . PIRSF PIRSF017215; ESCRT2_Vps22; 1; . SUPFAM SSF46785; SSF46785; 2; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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